Article
Characterization of 108 Genomic DNA Reference Materials for 11 Human Leukocyte Antigen Loci: A GeT-RM Collaborative Project.
The Journal of molecular diagnostics : JMD - 1 Sept 2018
Bettinotti Maria P, Ferriola Deborah, Duke Jamie L, Mosbruger Timothy L, Tairis Nikolaos, Jennings Lawrence, Kalman Lisa V, Monos Dimitri
Abstract excerpt
The highly polymorphic human leukocyte antigen (HLA) genes, located in the human major histocompatibility complex, encode the class I and II antigen-presenting molecules, which are centrally involved in the immune response. HLA typing is used for several clinical applications, such as transplantation, pharmacogenetics, and diagnosis of autoimmune disease. HLA typing is highly complex because of the homology of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
