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Article

Germ line predisposition to myeloid malignancies appearing in adulthood.

Expert review of hematology - 1 Aug 2018

Crysandt Martina, Brings Kira, Beier Fabian, Thiede Christian, Brümmendorf Tim H, Jost Edgar

Abstract excerpt

INTRODUCTION: Germ line predisposition to myeloid neoplasms has been incorporated in the WHO 2016 classification of myeloid neoplasms and acute leukemia. The new category of disease is named hereditary myeloid disorder (HMD). Although most myeloid neoplasms are sporadic, germ line mutations and familial predisposition can contribute to development of chronic myeloid diseases and acute myeloid leukemia. This...

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PMID: 29958021
DOI: 10.1080/17474086.2018.1494566

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