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ROCK Y-27632 Inhibitor, Ascorbic Acid, and Trehalose Increase Survival of Human Wharton Jelly Mesenchymal Stem Cells After Cryopreservation.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 Aug 2020

Kamalifar Sulmaz, Azarpira Negar, Sadeghi Ladan, Ghorbani-Dalini Sadegh, Nekoei Seideh Masoomeh, Aghdaie Mahdokht H, Esfandiari Elaheh, Azarpira Mohamad Reza

Abstract excerpt

OBJECTIVES: Wharton jelly mesenchymal stem cells are good candidates for application in different aspects of regenerative medicine, and their long-time banking is important. In this study, the effects of trehalose, ascorbic acid, and Y-27632 on proliferation and survival rate of these cells after cryopreservation were investigated. MATERIALS AND METHODS: Mesenchymal stem cells were isolated from human umbilical...

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PMID: 29957164
DOI: 10.6002/ect.2017.0101

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