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Article

Historical and Clinical Perspectives on Chromosomal Translocations.

Advances in experimental medicine and biology - 1 Jan 2000

Wilch Ellen S, Morton Cynthia C

Abstract excerpt

Chromosomal translocations, rearrangements involving the exchange of segments between chromosomes, were documented in humans in 1959. The first accurately reported clinical phenotype resulting from a translocation was that of Down syndrome. In a small percentage of Down syndrome cases, an extra 21q is provided by a Robertsonian translocation chromosome, either occurring de novo or inherited from a phenotypically...

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PMID: 29956287
DOI: 10.1007/978-981-13-0593-1_1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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