Rubella Viruses Shift Cellular Bioenergetics to a More Oxidative and Glycolytic Phenotype with a Strain-Specific Requirement for Glutamine.

doi:10.1128/JVI.00934-18

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Article

Rubella Viruses Shift Cellular Bioenergetics to a More Oxidative and Glycolytic Phenotype with a Strain-Specific Requirement for Glutamine.

Journal of virology - 1 Sept 2018

Bilz Nicole C, Jahn Kristin, Lorenz Mechthild, Lüdtke Anja, Hübschen Judith M, Geyer Henriette, Mankertz Annette, Hübner Denise, Liebert Uwe G, Claus Claudia

Abstract excerpt

The flexible regulation of cellular metabolic pathways enables cellular adaptation to changes in energy demand under conditions of stress such as posed by a virus infection. To analyze such an impact on cellular metabolism, rubella virus (RV) was used in this study. RV replication under selected substrate supplementation with glucose, pyruvate, and glutamine as essential nutrients for mammalian cells revealed its...

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PMID: 29950419
DOI: 10.1128/JVI.00934-18
PMCID: PMC6096829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.