Diagnosis of Richter transformation in chronic lymphocytic leukemia: histology tips the scales.

doi:10.1007/s00277-018-3390-x

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Article

Diagnosis of Richter transformation in chronic lymphocytic leukemia: histology tips the scales.

Annals of hematology - 1 Oct 2018

Federmann Birgit, Mueller Martin R, Steinhilber Julia, Horger Marius S, Fend Falko

Abstract excerpt

Development of diffuse large B-cell lymphoma in chronic lymphocytic leukemia, so-called Richter transformation (RT), occurs in 2-5% of patients and is associated with poor outcome. The clinical features of RT are fairly non-specific and unable to discriminate transformation from other mimics. In case of clinically suspected RT, a CT/MRT is recommended, and FDG-PET/CT may help to select the site of biopsy....

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PMID: 29947976
DOI: 10.1007/s00277-018-3390-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.