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Article

P450 oxidoreductase deficiency with maternal virilization during pregnancy.

Clinical and experimental obstetrics & gynecology - 1 Jan 2016

Nakanishi K, Yamashita A, Miyamoto T, Takeguchi R, Furuya A, Matsuo K, Tanahashi Y, Kawamura M, Sengoku K

Abstract excerpt

PURPOSE: The authors report on a rare case of maternal virilization during pregnancy caused by autosomal recessive P450 oxidore- ductase (POR) deficiency. MATERIALS AND METHODS: A 24-year-old primigravida developed a deepening voice and hirsutism in the second trimester. Prenatal ultrasonography failed to detect any fetal abnormality and fetal growth was normal. POR deficiency was suspected, but the mother...

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Source

Identifiers

PMID: 29944250

Genes

POR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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