Article
Influence of single nucleotide polymorphisms in pri-miR-124-1 and STAT3 genes on gastric cancer susceptibility.
British journal of biomedical science - 1 Oct 2018
Mirnoori S M, Shahangian S S, Salehi Zivar, Mashayekhi F, Talesh Sasani S, Saedi H S
Abstract excerpt
INTRODUCTION: MicroRNAs (miRNAs) are small ribonucleic acids that modulate the expression of downstream target genes. There is considerable evidence of their involvement in many malignancies, such as oesophageal and gastric. We hypothesised altered expressions of pri-miR-124-1 rs531564 and STAT3 rs1053023 polymorphisms in gastric cancer. MATERIALS AND METHODS: Genomic DNA was extracted from peripheral blood of...
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