Article
Comprehensive in-silico prediction of damage associated SNPs in Human Prolidase gene.
Scientific reports - 21 Jun 2018
Bhatnager Richa, Dang Amita S
Abstract excerpt
Prolidase is cytosolic manganese dependent exopeptidase responsible for the catabolism of imido di and tripeptides. Prolidase levels have been associated with a number of diseases such as bipolar disorder, erectile dysfunction and varied cancers. Single nucleotide polymorphism present in coding region of proteins (nsSNPs) has the potential to alter the primary structure as well as function of the protein. Hence,...
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