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Article

Propofol inhibits Wnt signaling and exerts anticancer activity in glioma cells

2 May 2018

Abstract excerpt

Aberrant activation of Wnt signaling is implicated in gliomagenesis. Propofol, the most commonly used intravenous anesthetic agent in clinics, exhibits potent antitumor activity in a variety of cancer cells through different mechanisms. However, the role of propofol on Wnt signaling and glioma cell growth remains to be fully elucidated. In the present study, propofol was identified as a potent inhibitor of Wnt...

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PMID: 29928428
DOI: 10.3892/ol.2018.8606

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