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Article

GJB3/GJB6 screening in GJB2 carriers with idiopathic hearing loss: Is it necessary?

Journal of clinical laboratory analysis - 1 Nov 2018

Chen Kaitian, Wu Xuan, Zong Ling, Jiang Hongyan

Abstract excerpt

BACKGROUND: Genetic analysis detected excessive mono-allelic recessive GJB2 mutations in individuals with idiopathic deafness; the remaining alleles in trans/cis are underdetermined. The aim of this study was to assess the contributions of variants in GJB3 or GJB6 to non-syndromic sensorineural hearing impairment (NSHI) in Chinese patients with mono-allelic GJB2 mutations. METHODS: The entire coding sequences of...

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Source

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Identifiers

PMID: 29926981
DOI: 10.1002/jcla.22592
PMCID: PMC6817113

Genes

GJB2
GJB3
GJB6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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