Article
Association of Polymorphisms in CYBA, SOD1, and CAT Genes with Type 1 Diabetes and Diabetic Peripheral Neuropathy in Children and Adolescents.
Genetic testing and molecular biomarkers - 1 Jul 2018
Snahnicanova Zuzana, Mendelova Andrea, Grendar Marian, Holubekova Veronika, Kostkova Martina, Pozorciakova Katarina, Jancinová Maria, Kasubova Ivana, Vojtkova Jarmila, Durdik Peter, Lasabova Zora, Ciljakova Miriam, Banovcin Peter
Abstract excerpt
AIMS: The aim of our study was to investigate possible associations between three SNPs: rs4673 in the CYBA gene; rs1041740 in the SOD1 gene; and rs1001179 in the CAT gene, and type 1 diabetes (T1D) or diabetic peripheral neuropathy (DPN) in T1D patients. MATERIALS AND METHODS: Allelic variants of the selected SNPs were determined by allelic discrimination assays in 114 T1D patients enrolled in the study group and...
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