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Article

New insights into the genetic diversity of Leishmania RNA Virus 1 and its species-specific relationship with Leishmania parasites.

PloS one - 1 Jan 2018

Cantanhêde Lilian Motta, Fernandes Flavia Gonçalves, Ferreira Gabriel Eduardo Melim, Porrozzi Renato, Ferreira Ricardo de Godoi Mattos, Cupolillo Elisa

Abstract excerpt

Cutaneous leishmaniasis is a neglected parasitic disease that manifests in infected individuals under different phenotypes, with a range of factors contributing to its broad clinical spectrum. One factor, Leishmania RNA Virus 1 (LRV1), has been described as an endosymbiont present in different species of Leishmania. LRV1 significantly worsens the lesion, exacerbating the immune response in both experimentally...

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Genetic Variation
Genome, Viral
Leishmania
Leishmaniasis
Phylogeny

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Species Specificity

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Identifiers

PMID: 29912912
DOI: 10.1371/journal.pone.0198727
PMCID: PMC6005476

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