Article
TYMS 2R3R polymorphism and DPYD [IVS]14+1G>A gene mutation in Mexican colorectal cancer patients.
Acta biochimica Polonica - 1 Jan 2018
Gallegos-Arreola Martha Patricia, Zúñiga-González Guillermo Moisés, Sánchez-López Josefina Yoaly, Cruz Alondra Yeraldi Naranjo, Peralta-Leal Valeria, Figuera Luis Eduardo, Puebla-Pérez Ana María, Ronquillo-Carreón Carlos Alberto, Puebla-Mora Ana Graciela
Abstract excerpt
OBJECTIVE: To examine the association between TYMS 2R3R polymorphism and DPYD [IVS]14+1G>A mutation by comparing healthy subjects with colorectal cancer (CRC) patients in the Mexican population. METHOD: Genotyping of the 2R/3R was performed by polymerase chain reaction (PCR) and [IVS]14+1G>A mutation by real-time PCR analysis. RESULTS: The observed frequencies of the TYMS 2R3R polymorphism and the -[IVS]14+1G>A...
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