Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche.

doi:10.1038/s41586-018-0213-0

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Article

Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche.

Nature - 1 Jun 2018

Kapp Friedrich G, Perlin Julie R, Hagedorn Elliott J, Gansner John M, Schwarz Daniel E, O'Connell Lauren A, Johnson Nicholas S, Amemiya Chris, Fisher David E, Wölfle Ute, Trompouki Eirini, Niemeyer Charlotte M, Driever Wolfgang, Zon Leonard I

Abstract excerpt

Haematopoietic stem and progenitor cells (HSPCs) require a specific microenvironment, the haematopoietic niche, which regulates HSPC behaviour1,2. The location of this niche varies across species, but the evolutionary pressures that drive HSPCs to different microenvironments remain unknown. The niche is located in the bone marrow in adult mammals, whereas it is found in other locations in non-mammalian...

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PMID: 29899448
DOI: 10.1038/s41586-018-0213-0
PMCID: PMC6093292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.