Sex differences influencing micro- and macrovascular endothelial phenotype in vitro.

doi:10.1113/JP276048

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Article

Sex differences influencing micro- and macrovascular endothelial phenotype in vitro.

The Journal of physiology - 1 Sept 2018

Huxley Virginia H, Kemp Scott S, Schramm Christine, Sieveking Steve, Bingaman Susan, Yu Yang, Zaniletti Isabella, Stockard Kevin, Wang Jianjie

Abstract excerpt

KEY POINTS: Endothelial dysfunction is an early hallmark of multiple disease states that also display sex differences with respect to age of onset, frequency and severity. Results of in vivo studies of basal and stimulated microvascular barrier function revealed sex differences that are difficult to ascribe to specific cells or environmental factors. The present study evaluated endothelial cells (EC) isolated...

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Identifiers

PMID: 29885204
DOI: 10.1113/JP276048
PMCID: PMC6117589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.