Article
Analysis of 3800-year-old Yersinia pestis genomes suggests Bronze Age origin for bubonic plague.
Nature communications - 8 Jun 2018
Spyrou Maria A, Tukhbatova Rezeda I, Wang Chuan-Chao, Valtueña Aida Andrades, Lankapalli Aditya K, Kondrashin Vitaly V, Tsybin Victor A, Khokhlov Aleksandr, Kühnert Denise, Herbig Alexander, Bos Kirsten I, Krause Johannes
Abstract excerpt
The origin of Yersinia pestis and the early stages of its evolution are fundamental subjects of investigation given its high virulence and mortality that resulted from past pandemics. Although the earliest evidence of Y. pestis infections in humans has been identified in Late Neolithic/Bronze Age Eurasia (LNBA 5000-3500y BP), these strains lack key genetic components required for flea adaptation, thus making...
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