Article
The zinc transporter ZIPT-7.1 regulates sperm activation in nematodes.
PLoS biology - 1 Jun 2018
Zhao Yanmei, Tan Chieh-Hsiang, Krauchunas Amber, Scharf Andrea, Dietrich Nicholas, Warnhoff Kurt, Yuan Zhiheng, Druzhinina Marina, Gu Sam Guoping, Miao Long, Singson Andrew, Ellis Ronald E, Kornfeld Kerry
Abstract excerpt
Sperm activation is a fascinating example of cell differentiation, in which immotile spermatids undergo a rapid and dramatic transition to become mature, motile sperm. Because the sperm nucleus is transcriptionally silent, this transition does not involve transcriptional changes. Although Caenorhabditis elegans is a leading model for studies of sperm activation, the mechanisms by which signaling pathways induce...
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