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Article

Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study.

American journal of respiratory and critical care medicine - 1 Dec 2018

Wan Emily S, Fortis Spyridon, Regan Elizabeth A, Hokanson John, Han MeiLan K, Casaburi Richard, Make Barry J, Crapo James D, DeMeo Dawn L, Silverman Edwin K

Abstract excerpt

RATIONALE: Increasing awareness of the prevalence and significance of Preserved Ratio Impaired Spirometry (PRISm), alternatively known as restrictive or Global Initiative for Chronic Obstructive Lung Disease (GOLD)-unclassified spirometry, has expanded the body of knowledge on cross-sectional risk factors. However, longitudinal studies of PRISm remain limited. OBJECTIVES: To examine longitudinal patterns of...

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Longitudinal Studies
Lung
Pulmonary Disease, Chronic Obstructive
Respiratory Function Tests
Smokers

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PMID: 29874098
DOI: 10.1164/rccm.201804-0663OC
PMCID: PMC6290948

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