Article
Polymorphism rs1385129 Within Glut1 Gene SLC2A1 Is Linked to Poor CD4+ T Cell Recovery in Antiretroviral-Treated HIV+ Individuals.
Frontiers in immunology - 1 Jan 2018
Masson Jesse J R, Cherry Catherine L, Murphy Nicholas M, Sada-Ovalle Isabel, Hussain Tabinda, Palchaudhuri Riya, Martinson Jeffrey, Landay Alan L, Billah Baki, Crowe Suzanne M, Palmer Clovis S
Abstract excerpt
Untreated HIV infection is associated with progressive CD4+ T cell depletion, which is generally recovered with combination antiretroviral therapy (cART). However, a significant proportion of cART-treated individuals have poor CD4+ T cell reconstitution. We investigated associations between HIV disease progression and CD4+ T cell glucose transporter-1 (Glut1) expression. We also investigated the association...
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