Two controls of cell proliferation underlie cancer relapse.

doi:10.1002/jcp.26597

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Article

Two controls of cell proliferation underlie cancer relapse.

Journal of cellular physiology - 1 Nov 2018

Pardee Arthur B, Li Chiang J

Abstract excerpt

Much progress has been made in understanding the basis of cancer. Current therapies can effectively shrink tumors. But they frequently relapse, metastasize to other locations, and are lethal. Effective therapies are very much needed for preventing this relapse. Creation of a eukaryotic organism commences with one original stem cell, a fertilized egg, which multiplies and differentiates. Mutations of normal stem...

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Identifiers

PMID: 29851079
DOI: 10.1002/jcp.26597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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