Article
Identification of early B cell precursors (stage 1 and 2 hematogones) in the peripheral blood.
Journal of clinical pathology - 1 Sept 2018
Kurzer Jason H, Weinberg Olga K
Abstract excerpt
Differentiating malignant B-lymphoblasts from early benign B cell precursors (hematogones) is a vital component of the diagnosis of B-lymphoblastic leukaemia. It has been previously reported that only late-stage B cell precursors circulate in the peripheral blood. Consequently, flow cytometric detection of cells with immunophenotypic findings similar to earlier stage precursors in the peripheral blood justifiably...
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