Notch3 protein expression in skin fibroblasts from CADASIL patients.

doi:10.1016/j.jns.2018.04.027

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Article

Notch3 protein expression in skin fibroblasts from CADASIL patients.

Journal of the neurological sciences - 15 Jul 2018

Qualtieri Antonio, Ungaro Carmine, Bagalà Angelo, Bianchi Silvia, Pantoni Leonardo, Moccia Marcello, Mazzei Rosalucia

Abstract excerpt

AIM: CADASIL is an inherited cerebrovascular disease caused by mutations in the NOTCH3 gene. Notch signaling is involved in a broad spectrum of function, from the cell proliferation to apoptosis. Thus far, because the molecular mechanism underlying the pathological alterations remains unclear and taking into account that fibroblasts contribute to the integrity of the vasculature, our aims was to establish whether...

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Identifiers

PMID: 29801872
DOI: 10.1016/j.jns.2018.04.027

Genes

NOTCH3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.