Article
Bovine pituitary homeobox 2 (PITX2): mRNA expression profiles of different alternatively spliced variants and association analyses with growth traits.
Gene - 30 Aug 2018
Zhang Sihuan, Xu Han, Kang Zihong, Cai Hanfang, Dang Ruihua, Lei Chuzhao, Chen Hong, Guo Xian, Lan Xianyong
Abstract excerpt
Pituitary homeobox 2 (PITX2) plays crucial roles in embryogenesis, ontogenesis, growth, and development via the Wnt/beta-catenin and POU1F1 pathways. To better understand the characteristics and genetic effects of the cattle PITX2 gene, we identified alternative PITX2 splicings, examined the effects of the spliced variants on mRNA expression levels in tissues, and then used association analyses to explore the...
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