Article
Gastrointestinal pathogens in anti-FH antibody positive and negative Hemolytic Uremic Syndrome.
Pediatric research - 1 Jul 2018
Togarsimalemath Shambhuprasad K, Si-Mohammed Ali, Puraswani Mamta, Gupta Aarti, Vabret Astrid, Liguori Sandrine, Mariani-Kurkdjian Patricia, Bagga Arvind, Dragon-Durey Marie-Agnes
Abstract excerpt
BACKGROUND: Prodromal symptoms are frequently reported in the atypical form of Hemolytic uremic syndrome (aHUS) suggesting implication of infectious triggers. Some pathogens may also play a role in the mechanisms of production of autoantibody directed against Factor H (FH), a complement regulator, leading to aHUS. METHODS: The presence of 15 gastrointestinal (GI) pathogens was investigated by using xTAG-based...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
