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Article

Influence of Confounding Factors on Radiation Dose Estimation Using In Vivo Validated Transcriptional Biomarkers

22 May 2018

Abstract excerpt

For triage purposes following a nuclear accident, blood-based gene expression biomarkers can provide rapid dose estimates for a large number of individuals. Ionizing-radiation-responsive genes are regulated through the DNA damage-response pathway, which includes activation of multiple transcription factors. Modulators of this pathway could potentially affect the response of these biomarkers and consequently...

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Share to Carcinogens and Genotoxicity Assessment
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29787434
DOI: 10.1097/hp.0000000000000844

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