Article
The developmental-genetics of canalization.
Seminars in cell & developmental biology - 1 Apr 2019
Hallgrimsson Benedikt, Green Rebecca M, Katz David C, Fish Jennifer L, Bernier Francois P, Roseman Charles C, Young Nathan M, Cheverud James M, Marcucio Ralph S
Abstract excerpt
Canalization, or robustness to genetic or environmental perturbations, is fundamental to complex organisms. While there is strong evidence for canalization as an evolved property that varies among genotypes, the developmental and genetic mechanisms that produce this phenomenon are very poorly understood. For evolutionary biology, understanding how canalization arises is important because, by modulating the...
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