Article
Genetics and Epigenetics Mechanism in the Pathogenesis of Behçet's Disease.
Current rheumatology reviews - 1 Jan 2019
Muhammad Jibran Sualeh, Ishaq Muhammad, Ahmed Khalid
Abstract excerpt
BACKGROUND: Behçet's Disease (BD) is characterized by numerous systemic manifestations and is known for its ability to affect both, arteries and the veins. However, the etiology of BD is only partially understood, and previous studies have demonstrated a role for genetic and epigenetic factors that contribute to disease pathophysiology. Several studies have implicated T cells and monocytes in the pathogenesis of...
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