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Article

MECHANISMS OF ENDOCRINOLOGY: Cell cycle regulation in adrenocortical carcinoma.

European journal of endocrinology - 1 Aug 2018

Pereira Sofia S, Monteiro Mariana P, Bourdeau Isabelle, Lacroix André, Pignatelli Duarte

Abstract excerpt

Adrenocortical carcinomas (ACCs) are rather rare endocrine tumors that often have a poor prognosis. The reduced survival rate associated with these tumors is due to their aggressive biological behavior, combined with the scarcity of effective treatment options that are currently available. The recent identification of the genomic alterations present in ACC have provided further molecular mechanisms to develop...

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Identifiers

PMID: 29773584
DOI: 10.1530/EJE-17-0976

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