Article
Novel NTRK1 mutations in Chinese patients with congenital insensitivity to pain with anhidrosis.
Molecular pain - 1 Jan 2000
Geng Xingzhu, Liu Yanshan, Ren XiuZhi, Guan Yun, Wang Yanzhou, Mao Bin, Zhao Xiuli, Zhang Xue
Abstract excerpt
Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disorder, characterized by loss of algesthesis and inability to sweat. CIPA is known to be caused by mutations in the neurotrophic tyrosine kinase receptor type 1 gene ( NTRK1). However, the details of NTRK1 mutations in Chinese CIPA patients remain unclear. In the present study, we recruited 36 CIPA patients from 34 unrelated...
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