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Article

Genomics and Epigenomics of Congenital Heart Defects: Expert Review and Lessons Learned in Africa.

Omics : a journal of integrative biology - 1 May 2018

Thomford Nicholas Ekow, Dzobo Kevin, Yao Nana Akyaa, Chimusa Emile, Evans Jonathan, Okai Emmanuel, Kruszka Paul, Muenke Maximilian, Awandare Gordon, Wonkam Ambroise, Dandara Collet

Abstract excerpt

Congenital heart defects (CHD) are structural malformations found at birth with a prevalence of 1%. The clinical trajectory of CHD is highly variable and thus in need of robust diagnostics and therapeutics. Major surgical interventions are often required for most CHDs. In Africa, despite advances in life sciences infrastructure and improving education of medical scholars, the limited clinical data suggest that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29762087
DOI: 10.1089/omi.2018.0033
PMCID: PMC6016577

Genes

MTHFR
GATA4
SCO2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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