Article
Influence of contraindicated medication use on cognitive outcome in Dravet syndrome and age at first afebrile seizure as a clinical predictor in SCN1A-related seizure phenotypes.
Epilepsia - 1 Jun 2018
de Lange Iris M, Gunning Boudewijn, Sonsma Anja C M, van Gemert Lisette, van Kempen Marjan, Verbeek Nienke E, Nicolai Joost, Knoers Nine V A M, Koeleman Bobby P C, Brilstra Eva H
Abstract excerpt
OBJECTIVE: Pathogenic variants in SCN1A can give rise to extremely variable disease severities that may be indistinguishable at their first presentation. We aim to find clinical features that can help predict the evolution of seizures into Dravet syndrome and clinical features that predict cognitive outcome in Dravet syndrome. We specifically investigate the role of contraindicated medication (CIM) as a possible...
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