Article
Functional signaling and gene regulatory networks between the oocyte and the surrounding cumulus cells
10 May 2018
Abstract excerpt
The maturation and successful acquisition of developmental competence by an oocyte, the female gamete, during folliculogenesis is highly dependent on molecular interactions with somatic cells. Most of the cellular interactions identified, thus far, are modulated by growth factors, ions or metabolites. We hypothesized that this interaction is also modulated at the transcriptional level, which leads to the...
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