Hemolytic uremic syndrome with multiple organ involvement secondary to complement factor H p.Arg1215X mutation.

Abstract excerpt

Complement mediated hemolytic uremic syndrome which is caused by excessive activation of the alternative complement system is a thrombotic microangiopathy. The disease frequently occurs as a result of mutations in the genes that regulates complement proteins. Complement factor H gene has the most common mutations. A nine-month-old male patient was transferred to pediatric intensive care unit with the diagnosis of...

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