Impact of a Missense Variation (p.S150R:AGC>AGG) in the XRCC2 Gene on Susceptibility to Colorectal Cancer.

doi:10.7754/Clin.Lab.2017.170717

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Article

Impact of a Missense Variation (p.S150R:AGC>AGG) in the XRCC2 Gene on Susceptibility to Colorectal Cancer.

Clinical laboratory - 1 Mar 2018

Sadat-Larijani Mona, Derakhshani Shaghayegh, Keshavarz-Pakseresht Behta, Nasri-Nasrabadi Ali, Shirkavand Atefeh, Sadat-Shandiz Seyed Ataollah, Baghbani-Arani Fahimeh

Abstract excerpt

BACKGROUND: The X-ray repair complementing defective repair in Chinese hamster cells 2 (XRCC2) is an important protein in response to DNA double-strand breaks (DSBs) in human cells. XRCC2, as a functional protein in the homologous recombination repair (HRR) process, has been identified to have several polymorphisms which might be associated with the risk of cancer. Therefore, we aimed to investigate a novel...

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PMID: 29739106
DOI: 10.7754/Clin.Lab.2017.170717

Genes

XRCC2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.