Article
Playing 'hide-and-seek' with factor H: game-theoretical analysis of a single nucleotide polymorphism.
Journal of the Royal Society, Interface - 1 May 2018
Hummert Sabine, Glock Christina, Lang Stefan N, Hummert Christian, Skerka Christine, Zipfel Peter F, Germerodt Sebastian, Schuster Stefan
Abstract excerpt
As a part of the complement system, factor H regulates phagocytosis and helps differentiate between a body's own and foreign cells. Owing to mimicry efforts, some pathogenic microorganisms such as Candida albicans are able to bind factor H on their cell surfaces and, thus, become similar to host cells. This implies that the decision between self and foreign is not clear-cut, which leads to a classification...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
