Article
Study on the association between drug‑resistance and gene mutations of the active efflux pump acrAB‑tolC gene and its regulatory genes.
Molecular medicine reports - 1 Jun 2018
Ma Quan-Ping, Su Liang, Liu Jing-Wen, Yao Ming-Xiao, Yuan Guang-Ying
Abstract excerpt
The aim of the present study was to investigate the correlation between the multi‑drug resistance of Shigella flexneri and the drug‑resistant gene cassette carried by integrons; in the meanwhile, to detect the associations between drug‑resistance and gene mutations of the active efflux pump acrAB‑tolC gene and its regulatory genes, including marOR, acrR and soxS. A total of 158 isolates were isolated from the...
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