Determination of cytoplasmic optineurin foci sizes using image correlation spectroscopy.

doi:10.1093/jb/mvy044

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Article

Determination of cytoplasmic optineurin foci sizes using image correlation spectroscopy.

Journal of biochemistry - 1 Sept 2018

Kitamura Akira, Shimizu Hiroki, Kinjo Masataka

Abstract excerpt

Optineurin (OPTN) plays an important role in membrane trafficking processes such as exocytosis and autophagy. The sizes and rate of formation of accumulated structures comprising OPTN, such as foci or inclusion bodies (IBs), are often disrupted by amyotrophic lateral sclerosis (ALS) and glaucoma-associated mutants of OPTN. Therefore, methods for the quantitative measurement of the size of the accumulated...

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Source

Open in PubMed

Identifiers

PMID: 29684153
DOI: 10.1093/jb/mvy044

Genes

OPTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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