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Kinetics of Circulating Cell-Free DNA for Biomedical Applications: Critical Appraisal of the Literature

23 Feb 2018

Abstract excerpt

Circulating cell-free DNA is considered as one of the major breakthroughs in the field of innovative diagnosis, used as a liquid biopsy. The kinetic parameters of a biomarker are mandatory to assess its usefulness as a diagnostic tool. Obtaining precise mathematical values for the kinetic parameters (e.g., half-life) is then crucial because it could be used for therapeutic monitoring as a prognostic factor....

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PMID: 29682327
DOI: 10.4155/fsoa-2017-0140

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