Article
Genetic and Environmental Contributions to the Covariation Between Cardiometabolic Traits.
Journal of the American Heart Association - 18 Apr 2018
Chen Xu, Kuja-Halkola Ralf, Chang Zheng, Karlsson Robert, Hägg Sara, Svensson Per, Pedersen Nancy L, Magnusson Patrik K E
Abstract excerpt
BACKGROUND: The variation and covariation for many cardiometabolic traits have been decomposed into genetic and environmental fractions, by using twin or single-nucleotide polymorphism (SNP) models. However, differences in population, age, sex, and other factors hamper the comparison between twin- and SNP-based estimates. METHODS AND RESULTS: Twenty-four cardiometabolic traits and 700,000 genotyped SNPs were...
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