Article
Tumor Syndromes Predisposing to Osteosarcoma.
Advances in anatomic pathology - 1 Jul 2018
Hameed Meera, Mandelker Diana
Abstract excerpt
Osteosarcoma (OS) is the most common primary bone tumor affecting predominantly adolescents and young adults. It accounts for about 5% of all childhood cancers. Although the majority of OSs are sporadic, a small percentage occur as a component of hereditary cancer syndromes. Early onset, bilateral, multifocal, and metachronous tumors suggest genetic predisposition. The inheritance patterns can be autosomal...
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