NIPS, a 3D network-integrated predictor of deleterious protein SAPs, and its application in cancer prognosis.

doi:10.1038/s41598-018-24286-2

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Article

NIPS, a 3D network-integrated predictor of deleterious protein SAPs, and its application in cancer prognosis.

Scientific reports - 16 Apr 2018

Wang Bo, Li Jing, Cheng Xi, Zhou Qiao, Yang Jingxu, Zhang Menghuan, Chen Haifeng, Li Jing

Abstract excerpt

Identifying deleterious mutations remains a challenge in cancer genome sequencing projects, reflecting the vast number of candidate mutations per tumour and the existence of interpatient heterogeneity. Based on a 3D protein interaction network profiled via large-scale cross-linking mass spectrometry, we propose a weighted average formula involving the combination of three types of information into a 'meta-score'....

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Identifiers

PMID: 29662108
DOI: 10.1038/s41598-018-24286-2
PMCID: PMC5902451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.