Article
A modified sequence capture approach allowing standard and methylation analyses of the same enriched genomic DNA sample.
BMC genomics - 13 Apr 2018
Olohan Lisa, Gardiner Laura-Jayne, Lucaci Anita, Steuernagel Burkhard, Wulff Brande, Kenny John, Hall Neil, Hall Anthony
Abstract excerpt
BACKGROUND: Bread wheat has a large complex genome that makes whole genome resequencing costly. Therefore, genome complexity reduction techniques such as sequence capture make re-sequencing cost effective. With a high-quality draft wheat genome now available it is possible to design capture probe sets and to use them to accurately genotype and anchor SNPs to the genome. Furthermore, in addition to genetic...
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