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Host shifts result in parallel genetic changes when viruses evolve in closely related species

12 Apr 2018

Abstract excerpt

Host shifts, where a pathogen invades and establishes in a new host species, are a major source of emerging infectious diseases. They frequently occur between related host species and often rely on the pathogen evolving adaptations that increase their fitness in the novel host species. To investigate genetic changes in novel hosts, we experimentally evolved replicate lineages of an RNA virus (Drosophila C Virus)...

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PMID: 29649296
DOI: 10.1371/journal.ppat.1006951

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