Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis.

Journal of translational medicine - 11 Apr 2018

Ikeno Yoshinobu, Seo Satoru, Iwaisako Keiko, Yoh Tomoaki, Nakamoto Yuji, Fuji Hiroaki, Taura Kojiro, Okajima Hideaki, Kaido Toshimi, Sakaguchi Shimon, Uemoto Shinji

Abstract excerpt

BACKGROUND: Surgical resection remains the mainstay of curative treatment for intrahepatic cholangiocarcinoma (ICC). Prognosis after surgery is unsatisfactory despite improvements in treatment and post-operative clinical management. Despite developments in the molecular profiling of ICC, the preoperative prediction of prognosis remains a challenge. This study aimed to identify clinical prognostic indicators by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholangiocarcinoma
Share to Fluorodeoxyglucose F18

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose Transporter Type 1

Share to Positron-Emission Tomography

Share to Preoperative Care

Share to Proto-Oncogene Proteins p21(ras)

Share to Survival Analysis

Share to Tumor Burden

Source

Open in PubMed Open full text

Identifiers

PMID: 29642912
DOI: 10.1186/s12967-018-1475-x
PMCID: PMC5896043

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis.PMID 29642912Read ↗

Genetic features associated with 18F-FDG uptake in intrahepatic cholangiocarcinomaSemantic proximity Read ↗

Correlation between 18F-FDG PET/CT intra-tumor metabolic heterogeneity parameters and KRAS mutation in colorectal cancer.Semantic proximity Read ↗

Clinicopathologic Features and Molecular Characteristics of Glucose Metabolism Contributing to ¹⁸F-fluorodeoxyglucose Uptake in Gastrointestinal Stromal Tumors.Semantic proximity Read ↗

Relationship between 18F-fluorodeoxyglucose accumulation and KRAS/BRAF mutations in colorectal cancer.Semantic proximity Read ↗

Relationship between PET/CT images and KRAS gene mutations in colorectal cancer in Vietnamese patients.Semantic proximity Read ↗

Predicting IDH mutation status of intrahepatic cholangiocarcinomas based on contrast-enhanced CT features.Semantic proximity Read ↗

KRAS mutation effects on the 2-[18F]FDG PET uptake of colorectal adenocarcinoma metastases in the liverSemantic proximity Read ↗

Relationship Between 18F-Fluorodeoxyglucose Uptake and V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog Mutation in Colorectal Cancer Patients: Variability Depending on C-Reactive Protein Level.Semantic proximity Read ↗

Regulation of 18F-FDG accumulation in colorectal cancer cells with mutated KRAS.Semantic proximity Read ↗

Correlation between PET/CT parameters and KRAS expression in colorectal cancer.Semantic proximity Read ↗

Value of contrast-enhanced CT texture analysis in predicting IDH mutation status of intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

Pretreatment 18F-FDG PET/CT Imaging Predicts the KRAS/NRAS/BRAF Gene Mutational Status in Colorectal CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.