Keratan Sulfate Phenotype in the β-1,3-N-Acetylglucosaminyltransferase-7-Null Mouse Cornea.

doi:10.1167/iovs.17-22716

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Keratan Sulfate Phenotype in the β-1,3-N-Acetylglucosaminyltransferase-7-Null Mouse Cornea.

Investigative ophthalmology & visual science - 1 Mar 2018

Littlechild Stacy L, Young Robert D, Caterson Bruce, Yoshida Hideyuki, Yamazaki Maya, Sakimura Kenji, Quantock Andrew J, Akama Tomoya O

Abstract excerpt

Purpose: Synthesis of keratan sulfate (KS) relies on coordinated action of multiple enzymes, including the N-acetylglucosamine-transferring enzyme, β-1,3-N-acetylglucosaminyltransferase-7 (β3GnT7). A mouse model deficient in β3GnT7 was developed to explore structural changes in KS and the extracellular matrix (ECM; i.e., the corneal stroma), elucidate the KS biosynthesis mechanism, and understand its role in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corneal Stroma
Share to Disease Models, Animal
Share to Mice
Share to Mice, Knockout

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to N-Acetylglucosaminyltransferases

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 29625490
DOI: 10.1167/iovs.17-22716
PMCID: PMC5869001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.