Article
Metabolomics activity screening for identifying metabolites that modulate phenotype.
Nature biotechnology - 5 Apr 2018
Guijas Carlos, Montenegro-Burke J Rafael, Warth Benedikt, Spilker Mary E, Siuzdak Gary
Abstract excerpt
Metabolomics, in which small-molecule metabolites (the metabolome) are identified and quantified, is broadly acknowledged to be the omics discipline that is closest to the phenotype. Although appreciated for its role in biomarker discovery programs, metabolomics can also be used to identify metabolites that could alter a cell's or an organism's phenotype. Metabolomics activity screening (MAS) as described here...
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