Article
Exploiting a Phage-Bacterium Interaction System as a Molecular Switch to Decipher Macromolecular Interactions in the Living Cell.
Viruses - 1 Apr 2018
Surányi Éva Viola, Hírmondó Rita, Nyíri Kinga, Tarjányi Szilvia, Kőhegyi Bianka, Tóth Judit, Vértessy Beáta G
Abstract excerpt
Pathogenicity islands of Staphylococcus aureus are under the strong control of helper phages, where regulation is communicated at the gene expression level via a family of specific repressor proteins. The repressor proteins are crucial to phage-host interactions and, based on their protein characteristics, may also be exploited as versatile molecular tools. The Stl repressor from this protein family has been...
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