Article
Genome-wide pleiotropy and shared biological pathways for resistance to bovine pathogens.
PloS one - 1 Jan 2018
Mahmoud M, Zeng Y, Shirali M, Yin T, Brügemann K, König S, Haley C
Abstract excerpt
Host genetic architecture is a major factor in resistance to pathogens and parasites. The collection and analysis of sufficient data on both disease resistance and host genetics has, however, been a major obstacle to dissection the genetics of resistance to single or multiple pathogens. A severe challenge in the estimation of heritabilities and genetic correlations from pedigree-based studies has been the...
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