Article
[CADASIL with cysteine-sparing NOTCH3 mutation manifesting as dissociated progression between cognitive impairment and brain image findings in 3 years: A case report].
Rinsho shinkeigaku = Clinical neurology - 25 Apr 2018
Tachiyama Keisuke, Shiga Yuji, Shimoe Yutaka, Mizuta Ikuko, Mizuno Toshiki, Kuriyama Masaru
Abstract excerpt
A 55-year-old man with no history of stroke or migraine presented to the clinic with cognitive impairment and depression that had been experiencing for two years. Neurological examination showed bilateral pyramidal signs, and impairments in cognition and attention. Brain MRI revealed multiple lacunar lesions and microbleeds in the deep cerebral white matter, subcortical regions, and brainstem, as well as diffuse...
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